logo

Chromosomes bearing amplified genes are a preferential

If you want to confirm some technical details before you order,
just need to send a message or e-mail: [email protected].
Then our professional sales staff will contact you within 2 hours.

Impact of rearrangements on function and ... - SpringerLi

Ottaggio L, Bonatti S, Cavalieri Z, Abbondandolo A (1993) Chromosomes bearing amplified genes are a preferential target of chemicals inducing chromosome breakage and aneuploidy.Mutat Res 301: 149–155. Google Scholar

Signs of Genomic Battles in Mouse Sex Chromosom

Indeed, old Y chromosomes have lost most of their ancestral genes in many taxa, are often highly repetitive, and have become partly or fully heterochromatic. Sex-biased transmission of sex chromosomes, on the other hand, makes the X and Y chromosome a battleground for sexual conflict.

Amplification of a plasmid bearing a mammalian replication .

Amplified genes in cancer cells reside on extrachromosomal double minutes (DMs) or chromosomal homogeneously staining regions (HSRs). We used a plasmid bearing a mammalian replication initiation region to model gene amplification. Recombination junctions in the amplified region were comprehensively identified and sequenced.

Mutation Research Letters | Vol 301, Issue 3, Pages 149 .

Pages 149-205 (March 1993) Download full issue. Previous vol/issue. Next vol/issue ... select article Chromosomes bearing amplified genes are a preferential target of chemicals inducing chromosome breakage and aneuploidy. Research article Full text access Chromosomes bearing amplified genes are a preferential target of chemicals inducing ...

Micronuclear entrapment of extrachromosomally amplified .

Read "Micronuclear entrapment of extrachromosomally amplified genes in irradiated tumor cells, International Journal of Radiation Oncology Biology Physics" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Signs of Genomic Battles in Mouse Sex Chromosomes: Ce

Y chromosomes are challenged by a lack of recombination and are transmitted to the next generation only via males. Sequencing of the mouse Y reveals how these properties drive opposing evolutionary processes: massive decay of ancestral genes and convergent acquisition and amplification of spermatid-expressed gene families on the X and Y chromosome.

Chromosome Territories - cshperspectives.cshlp.o

In Xi, Clemson et al. (2006) observed a preferential positioning of genes —irrespective of their transcriptional activity— at the nuclear periphery, whereas repetitive sequences were found rather in the nuclear interior. Such a distinct radial arrangement was not reported for Xa, possibly because of larger invaginations in Xa.

Chromosome rearrangements associated with CAD gene .

The marker chromosome of a PALA-resistant cell line containing a homogeneously staining region with amplified CAD gene was introduced into PALA-sensitive Chinese hamster cells by...

Zita Cavalieri's research wor

Zita Cavalieri's 5 research works with 184 citations and 37 reads, including: Induction of kinetochore-containing micronuclei by exogenous O6-methylguanine requires conversion of the methylated ...

Genome position and gene amplification - CO

(2001). A: New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays. Cancer Res (1989). Abbondandolo A: The presence of amplified regions affects the stability of chromosomes in drug-resistant Chinese hamster cells.

DTIC ADA339114: Amplified Genes in Breast Cancer .

We showed that extrachromosomally amplified genes in double minute chromosomes (DMs) are removed from tumor cells through preferential incorporation into...

Expression of Fragile Sites Triggers Intrachromosomal .

Expression of Fragile Sites Triggers Intrachromosomal ...

Isolation of Genes Amplified in Human Cancers by .

These anomalies are a manifestation of the intrinsic genomic instability of cancer cells, and it is presumed that overexpression of amplified genes confers a selective advantage on hsr bearing clones ( 1). Unfortunately, it is often difficult to identify the amplified genes in cells which contain hsr or dmin.

Citation - Comparative Cytogeneti

It can be achieved by choosing a plant with chromosomes bearing a prominent morphological feature, for example, a large somatic chromosome such as the Y chromosome in Silene. In Humulus japonicus, sex chromosomes are difficult to distinguish from autosomes at the mitotic metaphase fig (Grabowska-Joachimiak et al. 2011; Kim et al. 2008).

Isolation of Genes Amplified in Human Cancers by .

These anomalies are a manifestation of the intrinsic genomic instability of cancer cells, and it is presumed that overexpression of amplified genes confers a selective advantage on hsr bearing clones ( 1). Unfortunately, it is often difficult to identify the amplified genes in cells which contain hsr or dmin.

The Molecular Through Ecological Genetics of abnormal .

in a third or more of the X-linked 28s ribosomal genes (rDNA), and the failure of replicative selection favoring uninserted 28s genes in larval polytene tissues. The expression of this syndrome in males in ... The Y chromosomes extracted from nature are also polymorphic, with 16% of the Ys lacking the Y-specific rDNA marker.

NAVER Academic > Chromosomes bearing amplified genes .

Chromosomes bearing amplified genes are a preferential target of chemicals inducing chromosome breakage and aneuploidy Author Ottagio Laura, Bonati Stefania, Cavalieri ...

Sequencing the mouse Y chromosome reveals convergent gene .

Surviving ancestral Y genes are enriched for widely expressed, dosage-sensitive regulators of gene expression that may play crucial roles in Turner syndrome and sexual dimorphism in disease (Bellott et al., 2014). Second, both X and Y chromosomes have acquired and amplified genes independently of each other.

Cytogenetic and molecular genotyping in the allotetraploid .

Species of the Festuca and Lolium genera, as well as intergeneric Festuca × Lolium (Festulolium) hybrids, are valuable fodder and turf grasses for agricultural and amenity purposes worldwide. Festulolium hybrids can merge in their genomes agronomically important characteristics. However, in polyploid plants, especially in allopolyploids, the hybridization of divergent genomes could contribute ...

Chromosomes bearing amplified genes are a preferential .

Chromosomes bearing amplified genes are a preferential target of chemicals inducing chromosome breakage and aneuploidy Laura Ottagio, Stefania Bonati, Zita Cavalieri, Angelo Abbondandolo A.O.U. San Martino - IST, Istituto Nazionale Ricerca sul Cancro (GENOVA)