logo

The structural analysis of MARK4 and the exploration of

If you want to confirm some technical details before you order,
just need to send a message or e-mail: [email protected].
Then our professional sales staff will contact you within 2 hours.

The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progressi

Read "The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression, Molecular BioSystems" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Medscape | Mol Biosyst - Publication Informati

Exploration of the antagonist CP-376395 escape pathway for the corticotropin-releasing factor receptor 1 by random acceleration molecular dynamics simulations. ... Quantitative proteomic analysis ...

Publications Authored by Pranitha Jenardhanan | PubFac

Curr Top Med Chem 2019 ;19(6):467-485. Department of Biochemistry & Molecular Biology, School of Life Sciences, Pondicherry University, Puducherry, India.

MARK4 regulates NLRP3 positioning and inflammasome .

Excessive activation of the NLR family pyrin domain containing 3 (NLRP3) inflammasome is involved in many chronic inflammatory diseases, including cardiovascular and Alzheimer's disease. Here we show that microtubule-affinity regulating kinase 4 (MARK4) binds to NLRP3 and drives it to the microtubule-organizing centre, enabling the formation of one large inflammasome speck complex within a ...

RSC MB C3MB70591A 3. - ResearchGa

The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK ... we predicted the three dimensional structure for the kinase domain of MARK4 and analyzed its structural ...

mark4 | 3 H

mark4. Previous | Related Post. June 2, 2015. Time is Running Out to Get PTC Creo Simulate for 35% Off! PTC Creo Simulate is a structural, thermal and vibration analysis solution with a comprehensive set of finite elements analysis capabilities (FEA). Try it today — now at 35% off through June 26th!

MARK4 microtubule affinity regulating kinase 4 - Gene .

The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression. Jenardhanan P, Mannu J, Mathur PPJenardhanan P, et al. Mol Biosyst, 2014 Jul. PMID 24763618; Multiple localization of endogenous MARK4L protein in human glioma.

Structure and function of polarity-inducing kinase family .

Kinases of the MARK/Par-1 family of S/T protein kinases are regulators of diverse cellular processes in Caenorhabditis elegans, Drosophila, yeast, and mammalian cells. They are involved in nematode embryogenesis, epithelial cell polarization, cell signaling, and neuronal differentiation. MARK phosphorylates microtubule-associated proteins such as tau and is a key regulator of microtubule-based ...

SRK Structural Interpretation Assists Glencar’s Gold .

understanding of the structural controls SRK Structural Interpretation Assists Glencar’s Gold Discovery in Mali In March 2005, Glencar Mining plc engaged Toby Davis (SRK Perth) to develop structural models for mineralisation for a number of gold prospects they had identified in their Komana Project in southwest Mali.

Kinases as targets for chemical modulators: Structural .

The structural analysis of these inhibitory mechanisms will help us to circumvent the effects of toxicants as well as aid in developing better drugs and contraceptives with minimal nonspecific toxicities. ... The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: ...

StructureSolv

StructureSolver is an easy to use software package for integrated structural geology analysis in extensional and contractional tectonic regimes. It includes restoration, structural geology modeling and Area-Depth strain analysis.

Structural Analysis of Components of the Exploration and .

The goal of this project was to perform a stress analysis on the University of Alabama in Huntsville's SEDSAT1 (Students for the Exploration and Development of...

Stereochemical quality of protein structure coordinates .

Pranitha Jenardhanan, Jayakanthan Mannu and Premendu P. Mathur, The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression, Mol. BioSyst., 10, 7, (1845), (2014).

[PDF] miR-515-5 p controls cancer cell migration through .

Here, we show that miR-515-5p inhibits cancer cell migration and metastasis. RNA-seq analyses of both oestrogen receptor receptorpositive and receptor-negative breast cancer cells overexpressing miR-515-5p reveal down-regulation of NRAS, FZD4, CDC42BPA, PIK3C2B and MARK4 mRNAs. We demonstrate that miR-515-5p inhibits MARK4 directly 30 UTR interaction and that MARK4 knock-down mimics the effect ...

PDB 1ol7 citation summary ‹ Protein Data Bank in Europe .

The multifaceted allosteric regulation of Aurora kinase A. Levinson NM.Biochem J 475 2025-2042 (2018) ; On the molecular mechanisms of mitotic kinase activation. Bayliss R, Fry A, Haq T, Yeoh S. Open Biol 2 120136 (2012)

Differential Signature of the Centrosomal MARK4 Isoforms .

Pranitha Jenardhanan, Jayakanthan Mannu, and Premendu P. Mathur, “The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: A computational approach to obstruct the role of MARK4 in prostate cancer progression,” Molecular BioSystems, vol. 10, no. 7, pp. 1845–1868, 2014.

miR‐515‐5p controls cancer cell migration through MARK4 .

Jenardhanan P, Mannu J, Mathur PP (2014) The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression. Mol BioSyst 10: 1845 – 1868 Crossref CAS PubMed Web of Science® Google Scholar; 22.

JoVE | Peer Reviewed Scientific Video Journal - Methods .

Abstract The folkloric use of Nigerian Bonny-light crude oil (BLCO) in Niger Delta area of Nigeria is a common practice. There is increasing experimental evidence portending the adverse effects of BLCO an environmental toxicant on testicular function.

1 Applied Structural Geology in Exploration and Mini

• Describe best practices for structural data collection and analysis in mineral exploration and mining; • Provide sufficient information on the principal elements of structural processes to allow basic interpretations and analyses to be conducted; • Instill in attendees the confidence to start thinking about practical structural

The structural analysis of MARK4 and the exploration of .

The structural analysis of MARK4 and the exploration of specific inhibitors for the MARK family: a computational approach to obstruct the role of MARK4 in prostate cancer progression

Publications - Plant Biotechnology, TNAU, Coimbato

Structural analysis of MARK4 and exploration of specific inhibitors for MARK family: A computational approach to obstruct the role of MARK4 in Prostate Cancer progression. Molecular BioSystems, 10(7): 1845‐1868.